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Salt and pepper

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Nosebleeds. It was the nosebleeds. He would sneeze and his nose would bleed. Sometimes a little and sometimes a lot. Sometimes daily, but mostly it was every two or three days. Sometimes we could tell it was coming. His eyes would tell me, and, we would rush to put the ice pack on his neck. It was like he was hot.

The blood was bright red. Spatters. On the floor, sometimes on the wall. He was an old dog, fourteen. Was this what his old age would be like. Would he pass away from hemorrhaging? Would I be there to see him of on his final voyage? Except for the walk, he passed the time of day on his cushion. Difficult to wake up, hard of hearing, little or no appetite, breathing loudly and with difficulty. I would see his tiny stomach and rib cage fighting to inhale, battling to exhale.

At first, I thought he snored at night, but eventually I became convinced that he had trouble breathing. Each breath was deliberate, as if selected to be the last one. It woke me up at night. In the morning I would look at him to see if he giving me a sign that he wanted to give up. Instead, he sought out a cushion on the floor and continued sleeping noisily and deep.

Quite apart from Tobie, his nosebleeds, and his age, My Medico Veterinario was assessing what this TS&G did for people, for diabetics. I examined the bottle. There were two ingredients from plants. I e-mailed internet pictures of both trees to my medico veterinario. When I next went to see him, he brought me a few lots down from his clinic, walked into the backyard, saying to the owner, ‘You know what this tree is called?”
“Tronadora,” he replied instantly.
“Is it good for anything?”
“Oh yes. They use it for diabetics.”
“How do you know that?”
“A farmer in the hills told me.”

I researched each on the web. I was impressed. All of these quotes are from the Journal of Pharmaceutical and Biomedical Sciences.

“This interest in drugs of plant origin is due to several reasons, namely, conventional medicine can be inefficient (e.g. side effects and ineffective therapy), abusive and/or incorrect use of synthetic drugs results in side effects and other problems.”

“Tecoma stans leaves bark, and roots contain many biologically active chemicals, and extracts from those tissues have been used in traditional folk medicine to treat many diseases and conditions. [6] Leaves are used throughout Mexico and Central America for diabetes and urinary disorder control.”

“Chemical constituents of this botanical species are well known; numerous monoterpenic alkaloids have been identified [11-15] and among them, tecomanine and tecostanine possess hypoglycemic effects according to observations performed in animals.”

On reading this line, a dim light came on, with respect to Tobie. The review went on to describe the following effects Tecoma Stans has on humans:

Antidiabetic and Hypoglycemic activity
Anti-Inflammatory, Lipoxygenase, Xanthine Oxidase and Acetycholinesterase Inhibitory Activity
Wound Healing Potential: [37] The methanolic extract of Tecoma stans Linn (METS) leaf was evaluated for its wound healing potential in two different types of wound models viz., incision and excision at dose levels 100 and 200mg/kg. It exhibited marked reduction in the wound area when compared to controls and this activity is attributed to presence of phytoconstituents like phytosterols, triterpenes, glycosides, phenols, flavonoids, saponins, and tannins.

Now I was becoming agitated for my old dog. Where there is bleeding, there is a wound. There could be a chance that this would stop the bleeding. At about this time, Tobie had the haircut which revealed a tumor over his left eye. While I had seen him pass his paw over his eye, I gave it no special significance.

Antispasmodic effect:
Antimicrobial activity: [39,40] Three different extracts ethanol, methanol and water of Tecoma stans leaf was tested on bacteria (Pseudomonas fluorescens, Clavibacter michiganensis sub sp. michiganensis, Xanthomonas axanopodis pv. malvacearum, Staphylococcus aureus, E. coli, Pseudomonas aeruginosa and Klebsiella pneumonia) and was found to be effective . Phytochemical analysis revealed the presence of alkaloids, flavonoids, saponins, phenols, steroids, anthraquinones and tannins. The three extract fractions have showed highest total Phenolic content (177-216 mg gallic acid equivalent/g) which may be attributed to its antimicrobial activity. In another it has been reported that Tecoma stans was effective against Helicobacter pylori. The anti-H. pylori activity of methanolic extracts of the plants was determined by using the broth microdilution method.

Anti-proliferative and Antioxidant activity …Taken together, the novel compound 8 is effective as anti-proliferative agent against MCF-7 cells and as NO inhibitor, whereas 2 exhibited multi-functional properties as antioxidant and anti-proliferative agent against both solid tumor cell lines Hep-G2 and MCF-7 cells. …

Cytotoxic activity

Antifungal activity

Then there was the G, a tree, Guazima. From another report it briefly set out its properties which were described as:

Clinical data supports a use of the seeds for weight loss purposes. It has also been found useful as a(n): Analeptic, Antibacterial, Antidote, Comocladia, Antiherpetic, Antiprostaglandin, Antiseptic, Antiviral, Aperitif, Astringent, Bronchodilator, CNS-Stimulant, Cytotoxic, Depurative, Diaphoretic, Diuretic, Emollient, Hemostat, Pectoral, Respirtory stimulant, Stomachic, Uterotonic. In traditional medicine it has also been used to treat Alopecia, Anorexia, Asthma, Bacteria, Bleeding, Bronchosis, Cancer, Childbirth, Cold, Cough, Dermatosis, Diarrhea, Dislocation, Dysentery, Elephantiasis, Fever, Flu, Gonorrhea, Heatstroke, Hemorrhoid, Hepatosis, Herpes, Infection, Leprosy, Malaria, Nephrosis, Parasite, Pneumonia, Proctosis, Prostatosis, Pulmonosis, Rash, Shigella, Sore, Sore Throat, Staphylococcus, Syphilis, Virus, Water Retention. It can be ingested in the form of the crushed seeds soaked within water. Animal studies have supported pharmacological activity of: Antimicrobial, anticancer, hair-loss, anti-inflammation, antiulcer, ACE inhibitor, antioxidant, antidiabet, anticholesterol, hypotensive.

There was no doubt after reading this and other articles similar to this that Tobie would be given the medicine.

How would I administer it. I broke open a capsule, placed some of the ingredient on my tongue. It was the worst tasting substance I ever had in my mouth. My Medico Veterinario, too, tried to taste it. While more successful at getting it past his tongue than I, he said it seemed to go directly to his brain. I would not be able to have Tobie ingest it in his food.

I opened a capsule, poured out all but an eighth, stuffed some food in this portion of the capsule, and, forced it into his throat area. He swallowed. From the very next day, Tobie showed improvement. Within a week I had increased his dosage to one third of a capsule twice a day. One day, I noticed that his mouth fluttered like he had Parkinson’s. My Medico Veterinario suggested one time a day would be sufficient. He remains at this dosage. His nosebleeds declined to about once a week for several weeks, then to none for the past five weeks.

All the while this old dog continues to amaze me. His stamina, alertness, hearing and sight continue to improve. It’s not perfect. He is an old dog, but his quality of life is much improved.

And, I think, if does this for him, it will do it for me.

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